‘walking a tightrope’: Shirley Fitzgerald, Public Historian

Balancing Selection: Walking a Tightrope

Combining modern transgenic techniques with fitness measurements and enzyme activity assays, a new study demonstrates a habitat-dependent tradeoff between two alleles of a key detoxification enzyme in fruit flies. The elegant findings provide concrete, elusive evidence supporting a foundational and controversial theory about the maintenance of genetic variation.

Walking the Information Overload Tightrope

This chapter asks: What is information overload? At what levels of existence does it occur? Are there any features common to information overload at all these levels? What are information overload’s types? What are information overload’s current and future trends? What problems do they pose? How can they be addressed in both effective and morally justified ways? It argues that there is anarchy ...

Lecture 8: Edge Tracking – Walking the Tightrope

In the subcritical transition scenario, there is typically a regime where the linearly stable basic state coexists with the turbulent state. The simplest model of this is a 1D system ẏ = y(12 − y)(y − 1) where the basic state is y = 0, the ‘turbulent’ state is y = 1 and there is an intermediate state y = 12 which separates initial conditions which become turbulent (if y(0) > 12 then y(t) → 1 as...

Walking the tightrope on Medicare reform.

Naloxone in opioid poisoning: walking the tightrope.

Acute opioid intoxication and overdose are common causes of presentation to emergency departments. Although naloxone, a pure opioid antagonist, has been available for many years, there is still confusion over the appropriate dose and route of administration. This article looks at the reasons for this uncertainty and undertakes a literature review from which a treatment algorithm is presented.